Clinical Research

Kondalsamy-Chennakesavan S, van Vugt S, Sanday K, Nicklin J, Land R, Perrin L, Crandon A, Obermair A. Evaluation of tumor-free distance and depth of myometrial invasion as prognostic factors for lymph node metastases in endometrial cancer. Int J Gynecol Cancer. 2010 Oct;20(7):1217-21.

Harter P, Sehouli J, Reuss A, Hasenburg A, Scambia G, Cibula D, Mahner S, Vergote I, Reinthaller A, Burges A, Hanker L, Pölcher M, Kurzeder C, Canzler U, Petry KU, Obermair A, Petru E, Schmalfeldt B, Lorusso D, du Bois A. Prospective validation study of a predictive score for operability of recurrent ovarian cancer: the Multicenter Intergroup Study DESKTOP II. A project of the AGO Kommission OVAR, AGO Study Group, NOGGO, AGO-Austria, and MITO. Int J Gynecol Cancer. 2011 Feb;21(2):289-95.

Kondalsamy-Chennakesavan S, Gordon LG, Sanday K, Bouman C, De Jong S, Nicklin J, Land R, Obermair A. Hospital costs associated with adverse events in gynecological oncology. Gynecol Oncol. 2011 Apr;121(1):70-5. Epub 2010 Dec 18.

Obermair A, Mileshkin L, Bolz K, Kondalsamy-Chennakesavan S, Cheuk R, Vasey P, Wyld D, Goh J, Nicklin JL, Perrin LC, Sykes P, Janda M. Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma. Gynecol Oncol. 2011 Feb;120(2):179-84. Epub 2010 Dec 3.

Fearnley EJ, Marquart L, Spurdle AB, Weinstein P, Webb PM; Australian Ovarian Cancer Study Group and Australian National Endometrial Cancer Study Group. Polycystic ovary syndrome increases the risk of endometrial cancer in women aged less than 50 years: an Australian case-control study. Cancer Causes Control. 2010 Dec;21(12):2303-8. Epub 2010 Oct 17.

Janda M, Gebski V, Brand A, Hogg R, Jobling TW, Land R, Manolitsas T, McCartney A, Nascimento M, Neesham D, Nicklin JL, Oehler MK, Otton G, Perrin L, Salfinger S, Hammond I, Leung Y, Walsh T, Sykes P, Ngan H, Garrett A, Laney M, Ng TY, Tam K, Chan K, Wrede CD, Pather S, Simcock B, Farrell R, Obermair A. Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial. Lancet Oncol. 2010 Aug; 11(8):772-80.

Obermair A, Youlden DR, Young JP, Lindor NM, Baron JA, Newcomb P, Parry S, Hopper JL, Haile R, Jenkins MA. Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma. Int J Cancer. 2010 Dec; 127 (11): 2678-84.

Laky B, Janda M, Kondalsamy-Chennakesavan S, Cleghorn G, Obermair A. Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study. BMC Cancer. 2010 May 25;10:232.

Gordon LG, Obermair A. Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-audit. BMC Surg. 2010 Jan 27;10:4.

Bisseling KC, Kondalsamy-Chennakesavan S, Bekkers RL, Janda M, Obermair A. Depression, anxiety and body image after treatment for invasive stage one epithelial ovarian cancer. Aust N Z J Obstet Gynaecol. 2009 Dec;49(6):660-6.

Kondalsamy-Chennakesavan S, Bouman C, De Jong S, Sanday K, Nicklin J, Land R, Obermair A. Clinical audit in gynecological cancer surgery: development of a risk scoring system to predict adverse events. Gynecol Oncol. 2009 Dec;115(3):329-33. Epub 2009 Sep 15.

Crandon AJ, Obermair A. Advanced cytoreductive surgery: Asia Pacific perspective. Gynecol Oncol. 2009 Aug;114(2 Suppl):S15-21.

Levenback CF, van der Zee AG, Rob L, Plante M, Covens A, Schneider A, Coleman R, Solima E, Hertel H, Barranger E, Obermair A, Roy M. Sentinel lymph node biopsy in patients with gynecologic cancers Expert panel statement from the International Sentinel Node Society Meeting, February 21, 2008. Gynecol Oncol. 2009 Aug;114(2):151-6.

Obermair A, Tang A, Charters D, Weaver E, Hammond I. Survey of surgical skills of RANZCOG trainees. Aust N Z J Obstet Gynaecol. 2009 Feb;49(1):84-92.

Nicklin J, Perrin L, Crandon A, Land R, Nascimento M, Obermair A. Re: Guidelines for the use of recombinant activated factor VII in massive obstetric haemorrhage. Aust N Z J Obstet Gynaecol. 2008 Aug;48(4):447.

Walsh MD, Young J, Spurdle A, Obermair A. Lynch syndrome in women less than 50 years of age with endometrial cancer. Obstet Gynecol. 2008 Oct;112(4):943.

Obermair A, Cheuk R, Pak SC, Perrin L, Nicklin J, Crandon A, Land R, Chennakes SK, Janda M, Tripcony L. Disease-free survival after vaginal vault brachytherapy versus observation for patients with node-negative intermediate-risk endometrial adenocarcinoma. Gynecol Oncol. 2008 Sep;110(3):280-5.

Obermair A, Gebski V, Frumovitz M, Soliman PT, Schmeler KM, Levenback C, Ramirez PT. A phase III randomized clinical trial comparing laparoscopic or robotic radical hysterectomy with abdominal radical hysterectomy in patients with early stage cervical cancer. J Minim Invasive Gynecol. 2008 Sep-Oct;15(5):584-8.

Laky B, Janda M, Cleghorn G, Obermair A. Comparison of different nutritional assessments and body-composition measurements in detecting malnutrition among gynecologic cancer patients. Am J Clin Nutr. 2008 Jun;87(6):1678-85.

Walsh MD, Cummings MC, Buchanan DD, Dambacher WM, Arnold S, McKeone D, Byrnes R, Barker MA, Leggett BA, Gattas M, Jass JR, Spurdle AB, Young J, Obermair A. Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients. Clin Cancer Res. 2008 Mar 15;14(6):1692-700. Epub 2008 Feb 29.

Spurdle A, Webb P; Australian National Endometrial Cancer Study. Re: Excess of early onset multiple myeloma in endometrial cancer probands and their relatives suggests common susceptibility. Gynecol Oncol. 2008 Apr;109(1):153; author reply 154. Epub 2008 Jan 29.

Pak SC, Martens M, Bekkers R, Crandon AJ, Land R, Nicklin JL, Perrin LC, Obermair A. Pap smear screening history of women with squamous cell carcinoma and adenocarcinoma of the cervix. Aust N Z J Obstet Gynaecol. 2007 Dec;47(6):504-7.

Obermair A, Hiebl S. Laparoscopy in the treatment of ovarian tumours of low malignant potential. Aust N Z J Obstet Gynaecol. 2007 Dec;47(6):438-44. Review.

Janda M, Youlden DR, Baade PD, Jackson D, Obermair A. Elderly patients with stage III or IV ovarian cancer: should they receive standard care? Int J Gynecol Cancer. 2008 Sep-Oct;18(5):896-907. Epub 2007 Nov 6.

Obermair A. Preoperative serum CA125 in surgical stage 1 epithelial ovarian cancer. Gynecol Oncol. 2007 Nov;107(2):357-8. Epub 2007 Aug 13.

Smith CJ, Heeren M, Nicklin JL, Perrin LC, Land R, Crandon AJ, Obermair A. Efficacy of routine follow-up in patients with recurrent uterine cancer. Gynecol Oncol. 2007 Oct;107(1):124-9. Epub 2007 Jul 25.

Obermair A, Crandon A, Perrin L, Walsh T, Carraro M, Nicklin J. Randomized Trial of skin closure after laparotomy for gynaecological surgery. Aust NZ J Surg. 2007;77:460-463.

Beesley V, Janda M, Eakin E, Obermair A, Battistutta D. Lymphedema after gynecological cancer treatment : prevalence, correlates, and supportive care needs. Cancer 2007; 109:2607-2614.

Garrett AJ, Nascimento MC, Nicklin JL, Perrin LC, Obermair A. Total laparoscopic hysterectomy: the Brisbane learning curve. Aust NZ J Obstet Gynaecol. 2007;47:65-9.

Obermair A, Fuller A, Lopez-Varela E, van Gorp T, Vergote I, Eaton L, Fowler J, Quinn M, Hammond I, Marsden D, Proietto A, Carter J, Davy M, Tripcony L, Abu-Rustum N. A new prognostic model for FIGO stage 1 epithelial ovarian cancer. Gynecol Oncol. 2007;104:607-11.

Laky B, Janda M, Bauer J, Vavra C, Cleghorn G, Obermair A. Malnutrition among gynaecological cancer patients. Eur J Clin Nutr. 2007;61:642-6.

Janda M, Gebski V, Forder P, Jackson D, Williams G, Obermair A; LACE Trial Committee. Total laparoscopic versus open surgery for stage 1 endometrial cancer: the LACE randomized controlled trial. Contemp Clin Trials. 2006;27:353-63.

Obermair A, Manolitsas TP, Leung Y, Hammond IG, McCartney AJ. Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with endometrial cancer. Int J Gynecol Cancer 2005; 15:319-24.

Janda M, Obermair A, Cella D, Perrin LC, Nicklin JL, Ward BG, Crandon AJ, Trimmel M. The functional assessment of cancer-vulvar: reliability and validity. Gynecol Oncol. 2005; 97:568-75.

Paramasivam S, Tripcony L, Crandon A, Quinn M, Hammond I, Marsden D, Proietto A, Davy M, Carter J, Nicklin J, Perrin L, Obermair A. Prognostic importance of preoperative CA-125 in International Federation of Gynecology and Obstetrics stage I epithelial ovarian cancer: an Australian multicenter study.J Clin Oncol. 2005;23:5938-42.

Neppe C, Land R, Obermair A. Wrigley forceps to deliver a bulky uterus following a total laparoscopic hysterectomy for endometrial cancer. Aust N Z J Obstet Gynaecol. 2005; 45:444-5.

Carraro Nascimento M, Diane Cominos, Davies TNJ, Obermair A. Vulval Keratoacanthoma: A Case Report. Gynecol Oncol 2005; 97:674-6.

Carraro Nascimento M, Kelley A, Martitsch C, Weidner I, Obermair A. Postoperative analgesic requirements – Total Laparoscopic Hysterectomy vs. Vaginal Hysterectomy. Aust NZ J Obstet Gynaecol 2005; 45-140-3.

Lataifeh I, Nascimento MC, Nicklin JL, Perrin LC, Crandon AJ, Obermair A. Patterns of recurrence and disease-free survival in advanced squamous cell carcinoma of the vulva. Gynecol Oncol 2004;95:701-5.

Janda M, Obermair A, Cella D, Crandon AJ, Trimmel M. Vulvar cancer patients' quality of life: a qualitative assessment. Int J Gynecol Cancer 2004;14:875-81.

Janda M, Newman B, Obermair A, Woelfl H, Trimmel M, Schroeckmayr H, Widder J, Poetter R: Impaired quality of life in patients commencing radiotherapy for cancer. Strahlenther Onkol 2004;180:78-83.

Obermair A, Manolitsas TP, Leung Y, Hammond IG, McCartney AJ: Total laparoscopic hysterectomy for endometrial cancer: patterns of recurrence and survival. Gynecol Oncol 2004;92:789-93.

McCartney AJ, Obermair A.: Total laparoscopic hysterectomy with a transvaginal tube. J Am Assoc Gynecol Laparosc 2004;11:79-82.

Petru E, Pasterk C, Reich O, Obermair A, Winter R, Breitenecker G: Small-cell carcinoma of the uterus and the vagina: experience with ten patients. Arch Gynecol Obstet 2004

Hammond IG, Obermair A, Taylor JD, Lawrence-Brown M.: The overlay autogenous tissue (OAT) patch to control major intraoperative vascular injury in an ovine model. Gynecol Oncol 2004;94:560-3.

Hammond IG, Obermair A, Taylor JD, Lawrence-Brown M: The control of severe intraoperative bleeding using an overlay autogenous tissue (OAT) patch: case reports. Gynecol Oncol 2004;94:564-6.

Janda M, Obermair A, Cella D, Crandon AJ, Trimmel M: Vulvar cancer patients' quality of life: a qualitative assessment. Int J Gynecol Cancer 2004;14:875-81.

Dittrich Ch, Sevelda P, Salzer H, Obermair A, Speiser P, Breitenecker G, Schemper M, Kaider A; Austrian Ovarian Cancer Study Group: Lack of impact of platinum dose intensity on the outcome of ovarian cancer patients. 10-year results of a prospective randomised phase III study comparing carboplatin-cisplatin with cyclophosphamide-cisplatin. Eur J Cancer. 2003;39:1129-40. Erratum in: Eur J Cancer 2004;40:627.

Denison U, Baumann J, Peters-Engl C, Samonigg H, Krippl P, Lang A, Obermair A, Wagner H, Sevelda P: Incidence of anaemia in breast cancer patients receiving adjuvant chemotherapy. Breast Cancer Res Treat 2003;79:347-53.

Nather A, Mayerhofer K, Grimm C, Hefler L, Leodolter S, Obermair A, Joura EA: Thrombocytosis and anaemia in women with recurrent ovarian cancer prior to a second-line chemotherapy. Anticancer Res 2003;23:2991-4.

Obermair A, Ginbey P, McCartney AJ: Feasibility and safety of total laparoscopic radical hysterectomy. J Am Assoc Gynecol Laparosc 2003;10:345-9.

Preyer O, Obermair A, Formann E, Schmid W, Perrin LC, Ward BG, Crandon AJ, Nicklin J: The impact of positive peritoneal washings and serosal and adnexal involvement on survival in patients with stage IIIA uterine cancer. Gynecol Oncol 2002;86:269-73.

Obermair A, Cheuk R, Horwood K, Neudorfer M, Janda M, Nicklin JL, Perrin LC, Crandon AC: Anaemia before and during Concurrent Chemo-Radiotherapy in Patients with Cervical Carcinoma: Effect on Progression-Free Survival. Int J Gynecol Cancer 2003;13:633-9.

Preyer O, Obermair A, Formann E, Schmid W, Perrin LC, Ward PG, Nicklin JL, Crandon AJ: The impact of positive peritoneal washings and serosal and adnexal involvement on survival in patients with stage IIIA uterine cancer. Gynecol Oncol. 2002;86:269-273.

Clayton RD, Obermair A, Hammond IG, Leung Y, McCartney AJ: The Western Australian experience of the use of en bloc resection of ovarian cancer with concomitant rectosigmoid colectomy. Gynecol Oncol 2002; 84: 53-57.

Nicklin JL, Perrin LC, Obermair A, McConachie, A, Cominos D, : The significance of psammoma bodies on Nicklin JL, Perrin LC, Obermair A, McConachie I, Cominos D: The significance of cervical cytology smears. Gynecol Oncol 2001; 83: 6-9.

Obermair A, Hagenauer S, Tamandl D, Clayton RD, Nicklin JL, Perrin LC, Ward BG, Crandon AJ: Safety and efficacy of low anterior en bloc resection as part of cytoreductive surgery for patients with ovarian cancer. Gynecol Oncol 2001; 83:115-120.

Obermair A, Cheuk R, Horwood K, Janda M, Bachtiary B, Schwanzelberger B, Stoiber A, Nicklin J, Perrin L, Crandon A: Impact of Hemoglobin Levels before and during Chemo-Radiotherapy on the Response to Treatment in Patients with Cervical Carcinoma: Preliminary Results. Cancer 2001; 92: 903-908.

Umek W, Obermair A, Stutterecker D, Hausler G, Leodolter S, Hanzal E: Three-dimensional ultrasound of the fermal urethra: comparing transvaginal and transrectal scanning. Ultrasound in Obstet Gynecol 2001; 17: 425-430.

Bodner K, Bodner-Adler B, Obermair A, Windbichler G, Petru E, Mayerhofer S, Czerwenka K, Leodolter S, Kainz C, Mayerhofer K: Prognostic parameters in endometrial stromal sarcoma: a clinicopathologic study in 31 patients. Gynecol Oncol 2001; 81: 160-165.

Obermair A, Koller S, Crandon AJ, Perrin L, Nicklin JL: Primary Bartholin gland carcinoma: a report of seven cases. Aust N Z J Obstet Gynaecol 2001; 41: 78-81

Obermair A, Taylor K, Janda M, Nicklin J, Crandon A, Perrin L: Primary fallopian tube cancer: the Queensland experience. Int J Gynaecol Cancer 2001; 11: 69-72.

Obermair A, Geramou M, Tripcony L, Perrin L, Nicklin J, Crandon AJ: Peritoneal cytology: impact on disease-free survival in clincal stage I endometrioid adenocarcinoma of the uterus. Cancer Lett 2001; 164: 105-110.

Obermair A, Sevelda P: Impact of secondary cytoreductive surgery at second-look laparotomy in ovarian cancer patients. Acta Obstet Gynecol Scand 2001; 80: 432-436

Janda M, Gerstner N, Obermair A, Fuerst A, Wachter S, Dieckmann K, Ptter R: Quality of life changes during conformal radiation therapy for prostate carcinoma. Cancer 2000; 89: 1322-1328.

Janda M, Obermair A, Haidinger G, Waldhoer T, Vutuc C: Attitude and knowledge of Austrian women towards breast self examination. J Cancer Edu 2000; 15: 91-4.

Obermair A, Geramou M, Gucer F, Denison U, Graf AH, Kapshammer E, Medl M, Rosen A, Wierrani F, Neunteufel W, Frech I, Preyer O, Speiser P, Kainz C: Impact of hysteroscopy on the diseaese-free survival in clinically stage I endometrial cancer patients. Int J Gynecol Cancer 2000; 10: 275-279.

Hefler L, Mayerhofer K, Leibman B, Obermair A, Reinthaller A, Kainz C, Tempfer C: Tumor anemia and thrombocytosis in patients with vulvar cancer. Tumor Biol 2000; 21: 309-14.

Obermair A, Petru E, Windbichler G, Peters-Engl C, Graf AH, Stummvoll W, Kaider A, Kurschel S, Klbl H, Sevelda P: Pretreatment serum hemoglobin and survival in early stage epithelial ovarian cancer. Oncol Rep 2000; 7: 639-44.

Obermair A, Geramou M., Gcer F., Denison U., Graf A.H., Kapshammer E., Neunteufel W., Frech I, Kaider A., Kainz C. for the Austrian Gynecologic Oncology Study Group: Does hysteroscopy facilitate tumo rcell dissemination? Incidence of peritoneal cytology in patients with early-stage endometrial cancer following dilatation and curettage (D&C) versus hysteroscopy + D&C. Cancer 2000; 88: 139-143.

Obermair A., Geramou M., Gcer F., Denison U., Graf, AH., Kapshammer E., Medl M. Rosen A. Wierrani, F. Neunteufel W., Frech, I., Kaider A., Speiser P., Kainz C., Gerhard Breitenecker G. for the Austrian Gynecologic Oncology Study Group: Accuracy of the finding of a well differentiated tumor in endometrial cancer patients who undergo a Dilatation & Curettage with subsequent hysterectomy. Int J Gynecol Cancer 1999; 9: 383-386.

Peters-Engl C, Obermair A, Heinzl H, Buxbaum P, Sevelda P, Medl M: CA125 regression after two completed cycles of chemotherapy: lack of prediction for long-term survival in patients with advanced ovarian cancer. Br J Cancer 1999; 81: 662-666.

Jakesz R, Hausmanninger H, Haider K, Kubista E, Samonigg H, Gnant M, Manfreda D, Tschurtschenthaler G, Kolb R, Stierer M, Fridrik M, Mineritsch B, Steindorfer P, Mittelbck M, Steger G, and the Austrian Breast Cancer Study Group: Randomized trial of low-dose chemotherapy added to tamoxifen in patients with receptor-positive and lymph node-positive breast cancer. J Clin Oncol 1999; 17: 1701-1709.

Mayerhofer K, Obermair A, Windbichler G, Petru E, Kaider A, Hefler L, Czerwenka K, Leodolter S, Kainz C: Leiomyosarcoma of the uterus: a clinicopathologic multicenter study of 71 cases. Gynecol Oncol 1999; 74: 196-201

Obermair A, Speiser P, Thoma M, Kaider A, Salzer H, Dittrich C, Sevelda P: Prediction of toxicity by determining carboplatin exposure in patients with epithelial ovarian cancer treated with a combination of carboplatin and cisplatin. Int J Oncol 1998; 13: 1023-1030.

Obermair A, Handisurya A, Kaider A, Sevelda P, Klbl H, Gitsch G: The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients: a prospective review. Cancer 1998; 83: 726-31.

Jakesz R, Samonigg H, Gnant M, Kubista E, Steindorfer P, Hausmanninger H, Sevelda P, Tschurtschenthaler B, Fridrik M, Stierer M, Kolb R, Steger G and the Austrian Breast Cancer Study Group: Very low-dose adjuvant chemotherapy in steroid receptor negative stage I breast cancer patients. Eur J Cancer 1998; 34:66-70.

Obermair A, Binder M, Barrada M, Bancher-Todesca D, Asseryanis E, Kubista E: Onycholysis in patients treated with docetaxel. Ann Oncol 1998; 9: 230-231 (letter).

Bancher-Todesca D, Obermair A, Zeisler H, Prainsack D, Gitsch G, Reinthaller A: Management unvollstndig entfernter Lsionen nach Schlingenkonisation. Geburtshilfe und Frauenheilkunde 1997; 57: 458-462. [German]

Marth C, Windbichler G, Petru E, Dirschlmayer W, Obermair A, Czerwenka K, Mller-Holzner E, Dapunt O: Parity as an independent prognostic factor in malignant mixed mesodermal tumors of the endometrium. Gynecol Oncol 1997; 64: 121-125.

Obermair A, Hanzal E, Schreiner-Frech I, Buxbaum P, Bancher-Todesca D, Thoma M, Kurz C, Vavra N, Gitsch G, Sevelda P: Influence of delayed diagnosis on established prognostic factors in endometrial cancer. Anticancer Ressearch 1996; 16: 947-950.

Obermair A, Kurz C, Hanzal E, Bancher-Todesca D, Thoma M, Bodisch A, Kubista E, Kyral E, Kaider A, Sevelda P, Gitsch G: The influence of obesity on the disease-free survival in primary breast cancer. Anticancer Research 1995; 15: 2265-2270.

Obermair A, Vavra N, Kurz C, Helmer H, Sevelda P, Pehamberger K: Onycholysis in a case of high dose etoposide treatment for ovarian cancer: Gynecol Oncol 1995, 57: 436 (letter).

Sevelda P, Kurz Ch, Obermair A, Kubista E, Salzer H for the Austrian Cooperative Breast Cancer Study Group: Hormontherapie versus Chemo-Hormontherapie bei Patientinnen mit hormonrezeptorpositivem Mammakarzinom im Stadium I und II. Arch Gynecol Obstet 1993; 254: 895-897. [German]

Sevelda P, Mayerhofer K, Obermair A, Stolzlechner J, Kurz Ch: Thrombosis with paclitaxel. Lancet 1994; 343: 727 (letter).

Kurz Ch, Obermair A, Schemper M, Kubista E, Sevelda P: Beienflut Adipositas das rezidivfreie Intervall beim Mammakarzinom? Gynkol Geburtshilfliche Rundsch 1993; 33 (Suppl 1): 305-307. [German]

Ch, Salzer H, sterreichische Arbeitsgemeinschaft zur Therapie des Ovarialkarzinoms: Die Bedeutung der Platindosisintensitt in der Behandlung des epithelialen Ovarialkarzinoms. Wien Klin Wochenschr 1993; 105: 732-736. [German]

Sevelda P, Kurz Ch, Obermair A, Vavra N, Breitenecker G, Czerwenka K, Dittrich Ch, Salzer H, Oesterreichische Arbeitsgemeinschaft zur Therapie des Ovarialkarzinoms: Die Bedeutung der Platindosisintensitaet in der Behandlung des epithelialen Ovarialkarzinoma. Wien Klin Wochenschr 1993; 105:732-736 (German)